Creative Animodel Reveals Factors Collection That Affect the Pharmacokinetics
The metabolism of drugs in the body is generally carried out under the catalytic action of the enzyme. P450 enzyme in live is the mainly enzyme involved in drug pharmacokinetics in the body. The most important characteristic of P450 enzyme is that it can be induced or inhibited. At the same time, there are significant differences in race, age and sex, and the P450 enzyme has obvious polymorphism. Those effects will affect the content and activity of the enzyme so...
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