Lewes, DE -- (SBWIRE) -- 08/09/2018 -- Infantile Neuroaxonal Dystrophy - Market Insights, Epidemiology and Market Forecast-2027 report delivers an in-depth understanding of the disease, historical & forecasted epidemiology as well as the market trends of Infantile Neuroaxonal Dystrophy in the United States, EU5 (Germany, Spain, Italy, France and United Kingdom), and Japan.

The Report provides the current treatment practices, emerging drugs, market share of the individual therapies, current and forecasted market size of Infantile Neuroaxonal Dystrophy from 2016 to 2027 segmented by seven major markets. The Report also covers current treatment practice/algorithm, market drivers, market barriers and unmet medical needs to curate best of the opportunities and assess underlying potential of the market.

Geography Covered
- The United States
- EU5 (Germany, France, Italy, Spain and the United Kingdom)
- Japan

Study Period: 2016-2027

Infantile Neuroaxonal Dystrophy - Disease Understanding and Treatment Algorithm
Infantile Neuroaxonal Dystrophy (INAD) or PLA2G6-Associated Neurodegeneration (PLAN), which is also known as, Neurodegeneration with Brain Iron Accumulation (NBIA) and Seitelberger Disease, is an ultra-rare, devastating life-shortening neurodegenerative disorder that affects only a few hundred patients worldwide. It is caused by a genetic defect in the PLA2G6 housekeeping gene that removes damaged lipids from cells. Many children with INAD do not live beyond age 10, but some do survive into their teens or later ages.

The Publisher Infantile Neuroaxonal Dystrophy market report gives the thorough understanding of the Infantile Neuroaxonal Dystrophy by including details such as disease definition, classification, symptoms, etiology, pathophysiology, diagnostic trends. It also provides treatment algorithms and treatment guidelines for Infantile Neuroaxonal Dystrophy in the US, Europe, and Japan.

Infantile Neuroaxonal Dystrophy Epidemiology
The Infantile Neuroaxonal Dystrophy epidemiology division provide the insights about historical and current patient pool and forecasted trend for every 7 major countries. It helps to recognize the causes of current and forecasted trends by exploring numerous studies and views of key opinion leaders. This part of the Publisher report also provides the diagnosed patient pool and their trends along with assumptions undertaken.

The disease epidemiology covered in the report provides historical as well as forecasted epidemiology scenario of Infantile Neuroaxonal Dystrophy in the 7MM covering United States, EU5 countries (Germany, Spain, Italy, France and United Kingdom) and Japan from 2016-2027.

As per National Institutes of Health (USA), infantile neuroaxonal dystrophy is a very rare disorder. Its specific incidence is unknown. According to Great Ormond Street Hospital for Children NHS Foundation Trust, each pregnancy carries a 25 percent chance of the child being affected.

Infantile Neuroaxonal Dystrophy Drug Chapters
This segment of the Infantile Neuroaxonal Dystrophy report encloses the detailed analysis of marketed drugs and late stage (Phase-III and Phase-II) pipeline drugs. It also helps to understand the clinical trial details, expressive pharmacological action, agreements and collaborations, approval and patent details, advantages and disadvantages of each included drug and the latest news and press releases.

Although there is no treatment yet available that can stop the disease, drugs are be given to treat infections, pain relief and sedative drugs can be given if required, and feeding can be assisted. Oral or intrathecal baclofen can be given to those with atypical Infantile Neuroaxonal Dystrophy who have significant dystonia. Transdermal scopolamine patch can be given to reduce the volume of secretions in those with excessive drooling or difficulty controlling secretions. Because some individuals with PLA2G6-Associated Neurodegeneration (PLAN) have high brain iron and this disorder falls into the category of NBIA, the option of therapies to remove iron (chelation) is sometimes raised.

Infantile Neuroaxonal Dystrophy Market Outlook
The Infantile Neuroaxonal Dystrophy market outlook of the report helps to build the detailed comprehension of the historic, current and forecasted trend of the market by analyzing the impact of current therapies on the market, unmet needs, drivers and barriers and demand of better technology.

This segment gives a through detail of market trend of each marketed drug and late-stage pipeline therapy by evaluating their impact based on annual cost of therapy, inclusion and exclusion criteria's, mechanism of action, compliance rate, growing need of the market, increasing patient pool, covered patient segment, expected launch year, competition with other therapies, brand value, their impact on the market and view of the key opinion leaders. The calculated market data are presented with relevant tables and graphs to give a clear view of the market at first sight.

Currently, the pipeline for INAD is not so lucrative as there is only 1 drug, i.e., RT001 (Retrotope). But, the expected launch of RT001 in the future will create a positive impact on the INAD market. US FDA has granted Orphan Drug Designation for RT001 in the treatment of Phospholipase 2G6 (PLA2G6)-Associated Neurodegeneration (PLAN).

Infantile Neuroaxonal Dystrophy Drugs Uptake
This section focusses on the rate of uptake of the potential drugs recently launched in the market or will get launched in the market during the study period from 2016-2027. The analysis covers market uptake by drugs; patient uptake by therapies and sales of each drug.

This helps in understanding the drugs with the most rapid uptake, reasons behind the maximal use of new drugs and allows the comparison of the drugs on the basis of market share and size which again will be useful in investigating factors important in market uptake and in making financial and regulatory decisions.
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Infantile Neuroaxonal Dystrophy Report Insights
- Patient Population
- Therapeutic Approaches
- Pipeline Analysis
- Market Size and Trends
- Market Opportunities
- Impact of upcoming Therapies

Infantile Neuroaxonal Dystrophy Report Key Strengths
- 10 Years Forecast
- 7MM Coverage
- Epidemiology Segmentation
- Sub-type Segmentation
- Key Cross Competition
- Highly Analyzed Market
- Drugs Uptake

Infantile Neuroaxonal Dystrophy Report Assessment
- Current Treatment Practices
- Unmet Needs
- Pipeline Product Profiles
- Market Attractiveness
- Market Drivers and Barriers

Key Benefits
- This Publisher report will help to develop Business Strategies by understanding the trends shaping and driving Infantile Neuroaxonal Dystrophy market
- Organize sales and marketing efforts by identifying the best opportunities for Infantile Neuroaxonal Dystrophy market
- To understand the future market competition in the Infantile Neuroaxonal Dystrophy market.

Spanning over 120 pages "Infantile Neuroaxonal Dystrophy - Market Insights, Epidemiology and Market Forecast-2027" report covers Report Introduction, INAD: Market Overview at a Glance, Disease Background and Overview: INAD, Epidemiology and Patient Population, 7MM Total Prevalent Patient Population of INAD, Country Wise-Epidemiology of INAD Disease, Treatment Algorithm, Current Treatment, and Medical Practices, Unmet Needs, Emerging Drugs, INAD: 7 Major Market Analysis, The United States Market Outlook, EU-5 Countries: Market Outlook, Japan: Market Outlook, Market Drivers, Market Barriers, Appendix.

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