Albany, NY -- (SBWIRE) -- 07/07/2014 -- Over the past two decades, single-use bioreactors or disposable bioreactors have been in use in pharmaceutical industry that consists of a disposable bag instead of typical culture vessel made up of stainless steel or glass. On the other hand the disposable bag is usually made of three layers of plastic to offer mechanical stability and act as a gas barrier. The single-use bioreactor has several advantages over conventional bioreactors. Pharmaceutical companies usually produce different drugs using the same facility without compromising the quality and operate in various consecutive batches. In such situations, the main challenge is to ensure there are no remains over from earlier batches.

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The use of disposable bioreactor does not require any cleaning and sterilization. Other advantages include savings in cost and time. Disposable bioreactors are of several types based on means of agitating culture medium and its flexibility such as stirred rigid disposable bioreactors, stirred flexible disposable bioreactors, non-stirred flexible bioreactors and non-stirred disposable bioreactors. HyClone SUB Heavy Duty Tubing Clamp by Thermo Scientific, CellMarket Regular by Cellexus and WAVE Bioreactor 2/10EH by GE Healthcare are some of the commercially available disposable bioreactors in the market.

The market for single-use bioreactors is growing globally under the influence of advantages associated with the use of disposable reactors such as cost effectiveness, protection against cross contamination, time management and due to introduction of novel products. Geographically, North America and Europe represent the largest markets as majority of leading biopharmaceutical companies are located in these regions. The market is expected grow in Asia-Pacific and Latin America as many multinational biopharmaceutical companies are opening their manufacturing facilities in these regions are supposed to enhance the demand for disposable bioreactors. Some of the major players operating in the market for single-use bioreactors are GE Healthcare, Thermo Fisher Hyclone, PBS Biotech, Xcellerex, Sartorius Stedim Biotech, Merck Millipore, and Cellexus Limited.

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