Allentown, PA -- (SBWIRE) -- 02/03/2020 -- The two-page brochure from YMC featured below describes YMC-Triart Diol HILIC Columns. Diol-HILIC is ideal for separation of polar and hydrophilic compounds which are not easily retained by reversed-phase (C18, C8, and other) chromatography.
HPLC using HILIC mode is also useful for nucleosides and bases. The datasheet also includes a demonstration of a high resolution, ultra-fast separation of Phenformin hydrochloride and Metformin hydrochloride – with high resolution – in under 1 minute.
YMC-Triart Diol HILIC columns are available for HPLC (5 and 3 µm) and UHPLC (1.9 µm).
The HILIC (hydrophilic interaction chromatography) phase is based on an organic/inorganic hybrid particle synthesized with a dihydroxypropyl group. The USP designation for the stationary phase is L20.
The datasheet includes a comparison of the separation of L-Ascorbic acid and its stereoisomer (erythorbic acid) using reversed-phase (YMC-Triart C18) and HILIC separation modes. Even with 100% aqueous mobile phase, the reversed-phase column shows weak retention and non-ideal resolution between the analytes. Triart Diol-HILIC shows strong retention and improved resolution of these compounds with a mobile phase containing 90% organic solvent.
YMC-Triart is YMC's well-known family of hybrid particle HPLC columns and bulk stationary phases. There are nine distinct YMC-Triart stationary phases. YMC-Triart Diol-HILIC begins with the same organic/inorganic hybrid base particle as the other eight phases.
The base particle is synthesized with a dihydroxypropyl group to impart HILIC functionality. YMC-Triart Diol HILIC may be used across an extended pH range of 2-10. It also performs well at elevated temperatures. The wide-ranging mechanical, thermal, and chemical stability shown by Diol-HILIC provides the chromatographer with additional latitude to choose conditions beneficial to the separation, instead of making compromises due to limitations imposed by traditional stationary phases.
For a downloadable copy of the brochure, see:
https://www.ymcamerica.com/brochures/9097HILICdatasheet.pdf
Read more about YMC Columns and Stationary Phases at: https://www.ymcamerica.com
Interested parties can contact info@ymcamerica.com or call 888-341-8380.
About YMC America, Inc.
Established in 1980, YMC America, Inc. is worldwide full-service liquid chromatography company, which offers sales, technical product support, service, application assistance, purification services, contract synthesis and method development.
All YMC products are available worldwide through YMC's network of subsidiaries. This worldwide presence as a full-range chromatography supplier ensures that all YMC products are fully available and fully supported both locally and globally. See: https://www.ymcamerica.com/