Allentown, PA -- (SBWIRE) -- 04/23/2019 -- UHPLC Columns

Hybrid Particle HPLC phases

YMC-Triart Guard Columns for HPLC and UHPLC

Guard columns offer important functions in liquid chromatography. As the name implies, guard columns serve to protect the analytical column from contamination or damage, resulting in longer column life.

In research applications, during the process of method development, irreversible retention of some sample components can occur. With a guard column in place, the problem should occur on the guard, thus protecting the analytical column.

Columns with unwanted retained components can often be restored by flushing or cleaning in place (CIP) with a strong solvent. Restoring the performance of a guard column (simply swapping it out for a new one) is typically faster, easier, and more successful than restoring the performance of an analytical column.

For routine analyses, in addition to helping minimize problems associated with chemistry (i.e., retained compounds), guard columns can also help minimize the impact of physical issues at the head of the analytical column, such as a clogged frit or voiding at the column inlet. Guard columns are not substitutes for in-line filters or more rigorous sample prep (which should be used with "dirty" samples), but they can serve to help protect the frit and inlet of the analytical column.

Guard columns with clogged frits and/or voiding can often be restored with techniques such as reverse-flow flushing, an approach which can be tedious and does not always work.

For best performance, the stationary phase and column diameter of the guard column should closely match that of the analytical column. YMC-Triart is a family of stationary phases based on a hybrid particle and is offered in 7 distinct and overlapping phase chemistries – as well as multiple particle sizes. YMC-Triart itself demonstrates excellent tolerance of high pressure, high and low pH, and elevated temperatures.

In addition to a wide selection of stationary phase chemistries, YMC-Triart columns are available in a wide selection of diameters and separation scales: capillary LC, UHPLC, HPLC, Semi-Prep, and Prep. YMC offers guard column solutions for all of them.

Read more about YMC-Triart Guard Columns at: https://www.ymcamerica.com/ or contact: info@ymcamerica.com; call 888-341-8380.

About YMC America, Inc.
Established in 1980, YMC America, Inc. is worldwide full-service liquid chromatography company, which offers sales, technical product support, service, application assistance, purification services, contract synthesis and method development.

All YMC products are available worldwide through YMC's network of subsidiaries. This worldwide presence as a full-range chromatography supplier ensures that all YMC products are fully available and fully supported both locally and globally.

See: https://www.ymcamerica.com/